Mass torts
Depo-Provera is a contraceptive injection. The drug in it is medroxyprogesterone acetate. A study published in the BMJ in March 2024 reported a higher rate of surgically treated intracranial meningioma among women who used the injection for a year or more. Cases against Pfizer are grouped in one federal court as MDL 3140. Whether any one diagnosis is connected to the drug is not settled.
Nothing on this page says the injection caused anyone's tumor, and nothing here says anyone has a claim. Starting a case check does not mean we represent you.
Written by the Vetted Cases team
Posted August 15, 2026Updated August 15, 2026
Records, not recall
Injection dates may appear in the clinic file and, if a pharmacy dispensed the shot, its dispensing history. This page shows how to request both.
Where this comes from
We checked these original sources on August 15, 2026. Each link opens the source so you can read it for yourself.
Original links
JPML Transfer Order creating MDL No. 3140, February 7, 2025
In re: Depo-Provera Products Liability Litigation, MDL No. 3140
Roland N, et al. Use of progestogens and the risk of intracranial meningioma: national case-control study. BMJ 2024;384:e078078
DEPO-PROVERA (medroxyprogesterone acetate) injectable suspension, prescribing information
Where these cases stand
Court record read on August 15, 2026Updated when it changes.
Grouping cases together says nothing about whether any of them will succeed. When the legal facts change, this page changes with them.
The research
Sources read on August 15, 2026
People searching this subject are looking for the research as often as for the lawsuit. Here is what was published, what it reported, what its own authors say it cannot show, and what the approved label says.
Roland and colleagues, Use of progestogens and the risk of intracranial meningioma: national case-control study, published in the BMJ on March 27, 2024. It compared 18,061 women in France who had surgery for an intracranial meningioma with 90,305 matched women who did not.
It is a case-control study built on national health insurance records. It looks backward at what people were prescribed. Nobody was assigned a drug for the study.
For injectable medroxyprogesterone acetate, the drug in Depo-Provera, the study reported 9 exposed women among the 18,061 surgery cases and 11 among the 90,305 controls. That is an odds ratio of 5.55, with a confidence interval running from 2.27 to 13.56. The authors reported the excess risk was driven by use of a year or more.
An odds ratio compares two groups of people. It is not a personal risk, and it does not say what caused any one tumor.
The injection finding rests on 9 exposed women, which is a small number and is why the confidence interval is so wide. The study counted only meningiomas treated with surgery, so tumors that were watched rather than operated on are not in it. It was done in France, where this injection is prescribed far less often than in the United States. And an association measured across a population does not establish what happened to any one person.
Researchers publish limits like these themselves. A page that leaves them out is selling something.
The prescribing information for Depo-Provera CI, revised in December 2025, carries a Warnings and Precautions section on meningioma. It says cases of meningioma have been reported after repeated administration of medroxyprogesterone acetate, primarily with long term use, and it tells prescribers to monitor patients and to stop the drug if a meningioma is diagnosed.
A warning on a label is a safety instruction to doctors. It is not a finding that the drug caused any particular tumor.
A ratio compares two groups, not two people
It describes how often something turned up in one group of people against another. It is not a forecast for any one woman, and it does not say what happened inside anybody's head.
A wide interval means the study could not pin it down
A confidence interval is the range the researchers say the true figure probably sits in. When it is wide, that is the authors telling you the estimate is loose, usually because it rests on very few people.
An association is not a cause
Two things showing up together in records is where research starts, not where it ends. Turning that into a finding about one person is the work of a court, and here that work is not finished.
This is why the page will not tell you what the injection did to you. Nobody reading a population study can answer that, and the question of whether the drug can cause this tumor at all is still in front of the court.
If you only recently heard the word meningioma, start with its plain meaning and the report that names what was found.
A meningioma grows from the layers of tissue that cover the brain and the spinal cord. The National Cancer Institute calls it the most common primary brain tumor. Grade 1 meningiomas are the most common kind and their cells grow slowly.
Many are found by accident, on a scan ordered for headaches or after a fall. Being handed the word once, in a hallway, is the usual experience of it.
It usually turns up on an MRI or a CT scan, and the report is the part with the words in it. The report names what was found and where it sits. If nobody has handed you that report, you can ask the hospital or the imaging center for it, and you do not have to say why.
Not every one of these is operated on. Watching it with repeat scans is common, and a woman who was never wheeled into surgery still has a diagnosis and still has a record of it. If there was surgery, the pathology report on the tissue is the document that names it most precisely.
Read the plain description at the source (opens in a new tab)
This is general information, not medical advice. Ask your doctor or another qualified clinician about symptoms, diagnosis, and treatment. Medical care may have a cost; using this case check does not.
Three things describe the cases that have been filed. They are a description of other people's paperwork, not a set of requirements, and none of them is a test anybody passes on a web page.
The filings are about prolonged use rather than one or two shots, and the study reported that the excess it measured was driven by use of a year or more. The shot is usually given every three months, so a year is about four of them.
The word in the court's own description of these cases is meningioma. It is written down in the radiology report, and in the pathology report if there was surgery. Being told something was found is not the same as having the report that names it.
When the injections happened and when the diagnosis came are both part of the picture a lawyer reads. Approximate years are enough to start. The check ends with records that may confirm the dates.
Seeing your own history in that description settles nothing, and not seeing it settles nothing either. Whether a particular history and a particular diagnosis add up to a claim is what a lawyer decides after reading the records, and it is the one question this page refuses to answer.
Four questions, no form
Four questions. It organises what you already know, sets it beside what the filings have in common, and tells you which records to go and find.
This does not tell you whether you have a case, what a case is worth, or how long you have. Those answers come from a lawyer who has read your records.
Step 1 of 4. Did you receive Depo-Provera injections?
If you are not sure, say so. The next screen shows what it is called on a pharmacy or clinic record.
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A quick reality check
This page cannot decide whether Depo-Provera caused a diagnosis, whether anyone qualifies, case value or a legal deadline. A group-level study and a federal docket do not decide one person's medical or legal questions. Those require the full records and a licensed attorney's review.
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